Scleroderm \Scler"o*derm\ (? or ?; 277), n. [Gr. sklhro`s hard + de`rma skin: cf. F. scl['e]roderme.] (a) (Zo["o]l.) One of a tribe of plectognath fishes ({Sclerodermi}) having the skin covered with hard scales, or plates, as the cowfish and the trunkfish. (b) One of the Sclerodermata. (c) Hardened, or bony, integument of various animals.