Mediate \Me"di*ate\, v. i. [imp. & p. p. {Mediated}; p. pr. & vb. n. {Mediating}.] [LL. mediatus, p. p. of mediare to mediate. See {Mediate}, a.] 1. To be in the middle, or between two; to intervene. [R.] 2. To interpose between parties, as the equal friend of each, esp. for the purpose of effecting a reconciliation or agreement; as, to mediate between nations.