Lophiomys \Lo*phi"o*mys\, n. [NL., fr. Gr. lofia` a mane, bristly ridge + my^s a mouse.] (Zo["o]l.) A very singular rodent ({Lophiomys Imhausi}) of Northeastern Africa. It is the only known representative of a special family ({Lophiomyid[ae]}), remarkable for the structure of the skull. It has handlike feet, and the hair is peculiar in structure and arrangement.