Duplication \Du`pli*ca"tion\, n. [L. duplicatio: cf. F. duplication.] 1. The act of duplicating, or the state of being duplicated; a doubling; a folding over; a fold. 2. (Biol.) The act or process of dividing by natural growth or spontaneous action; as, the duplication of cartilage cells. --Carpenter. {Duplication of the cube} (Math.), the operation of finding a cube having a volume which is double that of a given cube.